Bayer Schering Testosterone Composition 10amp 250mg/ml

Description

Bayer Schering's Testosterone Composition, particularly in the form of Primoteston Depot, contains testosterone enantate. Here are the essential details:

1. Composition:

   - Each ampule of Primoteston Depot comprises 250 mg of testosterone enantate (equivalent to approximately 180 mg of testosterone) in a clear, yellowish oily solution for injection.

   - The formulation also includes benzyl benzoate and castor oil as excipients.

2. Pharmacology:

   - Testosterone enantate exhibits a depot effect, allowing for extended intervals between injections.

   - It offers a prolonged and potent androgenic impact.

   - The duration of action of 1 mL Primoteston Depot is approximately 2-4 weeks, depending on the individual's initial hormonal status.

3. Indications:

   - Primoteston Depot is utilized for androgen replacement therapy in males with confirmed testosterone deficiency.

4. Contraindications:

   - Avoid use in individuals with prostatic carcinoma, mammary carcinoma in males, and hypercalcemia accompanying malignant tumors.

   - History of or existing liver tumors is also a contraindication.

   - Hypersensitivity to any of the ingredients warrants caution.

5. Precautions:

   - Maintain serum testosterone levels within the reference range for the relevant age group.

   - Androgens should not be used to enhance muscular development in healthy individuals.

   - Regular prostate examinations are advisable.

   - Periodic monitoring of hemoglobin and hematocrit is recommended to detect polycythemia.

   - Exercise caution in patients with thrombophilia.

   - Consider hepatic tumors in the differential diagnosis for upper abdominal complaints.