Letrozole

Letrozole, marketed under the brand name Femara, stands as an oral tablet prescribed for managing breast cancer in postmenopausal women. Here are salient insights into letrozole:

Mechanism of Action:

Letrozole functions by diminishing estrogen levels in postmenopausal women.

It impedes the growth of specific types of breast tumors reliant on estrogen for proliferation.

Applications:

Breast Cancer Management: Letrozole finds application in the treatment of breast cancer among postmenopausal women.

Transition from Tamoxifen: It is commonly administered to individuals who have undergone a five-year course of tamoxifen therapy.

Side Effects:

Common adverse effects may include:

Hot flashes

Headaches

Bone and joint discomfort

Excessive perspiration

Elevated cholesterol levels

Warnings and Precautions:

Pregnancy: Refrain from utilizing letrozole if pregnant, as it may pose risks to fetal well-being.

Liver Impairment: Exercise caution with letrozole usage in the presence of liver disease.

Breastfeeding: Avoid breastfeeding while undergoing letrozole treatment.

Adherence to these insights concerning letrozole ensures informed decision-making and enhances safety under the guidance of healthcare professionals.